Gene Islands Integrated into tRNA Genes Confer Genome Diversity on a Pseudomonas aeruginosa Clone
نویسندگان
چکیده
Karen D. Larbig, Andreas Christmann, André Johann, Jens Klockgether, Thomas Hartsch,† Rainer Merkl, Lutz Wiehlmann, Hans-Joachim Fritz, and Burkhard Tümmler* Klinische Forschergruppe, Medizinische Hochschule Hannover, Hannover, and Abteilung Molekulare Genetik und Präparative Molekularbiologie, Institut für Mikrobiologie und Genetik, and Göttingen Genomics Laboratory, Universität Göttingen, Göttingen, Germany
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Gene islands integrated into tRNA(Gly) genes confer genome diversity on a Pseudomonas aeruginosa clone.
Intraclonal genome diversity of Pseudomonas aeruginosa was studied in one of the most diverse mosaic regions of the P. aeruginosa chromosome. The ca. 110-kb large hypervariable region located near the lipH gene in two members of the predominant P. aeruginosa clone C, strain C and strain SG17M, was sequenced. In both strains the region consists of an individual strain-specific gene island of 111...
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